Clinical Guide to Angio-OCT: Non Invasive, Dyeless OCT Angiography (Hardback)  | Released: 10 Dec 2014

• Shows every day OCT user the clinical utility of OCT angiography.• Presents the principles of Angio-OCT.• Presents SSADA algorithms and its applications, choroidal neovascularization (CNV), optic disk disorders and glaucoma.• Proposes the new terminology necessary to study this new technique.• Includes description of the vascular anatomy of retina and choroid, general syndromes and clinical signs.• Presents technological or scientific Angio-OCT progresses and their clinical applications.• Discusses clinical possibilities of OCT Angiography.• Guides the basic ophthalmologists or technicians to understand the new imaging typical and atypical aspects. About the AuthorBruno Lumbroso MD David Huang MD PhD Yali Jia PhD James G Fujimoto PhD Marco Rispoli MDTable of Contents: 1. Principles of Optical Coherence Tomography-Angiography 1 Bruno Lumbroso, Marco Rispoli Limitations of Optical Coherence Tomography-Angiography 2 Limitations of Optical Coherence Tomography 2 Retinal Fluorangiography and Optical Coherence Tomography-Angiography 3 2. Optical Coherence Tomography-Angiography: New Clinical Terminology 5 James G Fujimoto, Bruno Lumbroso, Marco Rispoli Angio-OCT Clinical Terminology 5 3. Split-Spectrum Amplitude-Decorrelation Angiography 8 David Huang, Yali Jia 4. Solving the Practical Problems of Optical Coherence Tomography-Angiography 10 Marco Rispoli, Bruno Lumbroso Mistakes to be Avoided 10 5. Optical Coherence Tomography-Angiography of a Normal Retina: The Anatomy of Blood Supply in the Retina 12 Maria Cristina Savastano, Bruno Lumbroso, Marco Rispoli Posterior Pole 12 Macular Area 12 Arteries and Retinal Veins 12 6. Analysis and Synthesis: Analysis and Interpretation of a Pathological Optical Coherence Tomography-Angiography 16 Bruno Lumbroso, Marco Rispoli Analytic Steps 16 Analysis of Neovascular Membranes 21 Synthesis 22 7.1 Clinical Applications: Aspects of OCT SSADA Angiography in Eye Disorders 23 Bruno Lumbroso, Marco Rispoli, Maria Cristina Savastano, Adil El Maftouhi, Leonardo Mastropasqua, Luca Di Antonio, Giovanni Staurenghi Age-Related Retinal Anomalies 23 Retinal Anomalies and Coat’s Disease 23 Retinal Anomalies in Angiomatosis 24 Retinal Superficial Anomalies in Macular Pucker 25 Macroaneurysm 25 Angio-OCT, Non Invasive, Dyeless OCT Angiography Diabetic Patients without Retinopathy 30 Branch Retinal Vein Occlusions 30 Recent or Long-Lasting Retinal Ischemias 32 Diabetic Retinopathy 35 Proliferative Diabetic Retinopathy 45 CNV: Neovascular Membranes in ARMD 47 Neovascular Membranes in Myopic Eyes 48 Idiopathic Polypoidal Choroidal Vasculopathy 49 Geographic or Atrophic Macular Degeneration 59 Optic Disk Disorders 59 7.2 Clinical Applications: Optical Coherence Tomography-Angiography of Choroidal Neovascularization in Age-Related Macular Degeneration 60 Yali Jia, David Huang 8. Optical Coherence Tomography-Angiography of Optic Disk and Peripapillary Retinal Perfusion in Glaucoma 64 Yali Jia, David Huang 9. Fluorescein Angiography and Optical Coherence Tomography-Angiography: Advantages and Disadvantages 68 Bruno Lumbroso, Marco Rispoli General Fluorangiography Advantages 68 General Fluorangiography Disadvantages 68 Fluorangiography Imaging Advantages 68 General Angio-OCT Disadvantages 69 General Advantages of Angio-OCT Imaging 69 Angio-OCT Imaging Advantages 69 Angio-OCT Disadvantages 69 Other Non Invasive Techniques 70 10. Reporting an Optical Coherence Tomography-Angiography 71 Marco Rispoli Analytic Steps 71 Case Reports 71 11. Future Ultrahigh Speed Swept-Source OCT Technology and OCT-Angiography 75 Nadia K Waheed, Woo Jhon Choi, Jay S Duker, James G Fujimoto Swept-Source Optical Coherence Tomography for Ultrahigh Speeds 75 Optical Coherence Tomography-Angiography 77 Imaging the Choriocapillaris 77 Optical Coherence Tomography-Angiography in Diabetes 79 Optical Coherence Tomography-Angiography in Dry Age-Related Macular Degeneration 81 Index 85 Prelims.indd 12 9/6/2014 10:38:44 AMIntroduction In the last few years, structural and functional optical coherence tomography (OCT) technology has seen new and revolutionary developments. The most important of which is arguably an OCT angiography (Angio-OCT). Angio-OCT is already playing an important role in clinical ophthalmology as a new, non invasive and dyeless diagnostic tool, which serves as an adjunct to, or even a replacement for fluorescein and indocyanine green (ICG) angiographies. Angio-OCT is bringing multiple technical and clinical improvements in the study of retinal diseases, glaucoma and optic nerve disorders. It enables rapid, high-resolution visualization of vascular structure in three dimensions as well as ease of repeated imaging. In the Clinical Guide to Angio-OCT (Non Invasive, Dyeless OCT Angiography), we offer a step-by-step guide for interpreting clinical images and data acquired by Angio-OCT. In this book, we present a logical method for interpreting ophthalmic images. The first phase is analytic. The second phase combines elementary components to synthesize the data, allowing an accurate diagnosis and treatment decision. We also update OCT terminology in order to have a standardized approach for assessing Angio-OCT features. The book explains similarities and differences between this new imaging method, and the classical fluorescein and ICG angiographies. Very soon new advances in technology will further improve Angio-OCT imaging, making day-to-day clinical work easier. We trust the book will help ophthalmologists, residents, ophthalmic technicians and optometrists to understand and appreciate the new possibilities offered by the latest Angio-OCT imaging technologies. Bruno Lumbroso David Huang Yali Jia James G Fujimoto Marco Rispoli Prelims.indd 13 9/6/2014 10:38:44 AM