Miniaturization and Mass Spectrometry (Hardback)  | Released: 03 Dec 2008

The explosion in the late 20th century of the field of analytical chemistry and particularly for biological purposes- has led to a need for fast, integrated, portable, more reliable and more sensitive tools that could handle reduced amount of samples. Microfluidics and lab-on-a-chip devices provide a good answer to this quest to miniaturized and enhanced analysis and they lend themselves well to mass spectrometric detection. This book illustrates this trend and discusses the analysis of large but frail molecules, e.g DNA, proteins and oligosaccharides. Essential reading for anyone with an interest in this field.About the Author: Sverine Le Gac got her Ph.D. at the University of Sciences and Technologies of Lille (France) in 2004 on the topic of microfluidic systems for mass spectrometry analysis and proteomics applications. Since 2005 she has been working in BIOS, The Lab-on-a-Chip group led by Pr. Van den Berg at the University of Twente. Her current research focuses on microfluidics applications of cell analysis. Since January 2008 she has been appointed as assistant professor in the ame group to lead the research topic "from cell on a chip towards lab-in-a-cell applications. Albert van den Berg leads The Lab-on-a-Chip Group at the University of Twente. His current research interests focus on microanalysis systems and nanosensors, nanofluidics and single cells on chips. He received the Simon Stevin Master award from the Dutch Technical Science foundation (STW) in 2002 and, in the following year, was appointed captain of the Nanofluidics Flagship within the national nanotechnology program, Nanoned.